Research Article

Exploring the Mechanism on the Medullary Visceral Zone Inhibiting the Cholinergic Anti-inflammatory Pathway Induced by Sepsis

Table 2

Time and frequency domain and nonlinear analysis of HRV among different groups.

Control groupSham groupModel groupGTS-21 groupMLA group

SDNN (ms)
RMSSD (ms)
TP (ms2)
VLF (ms2)
LF (ms2)
HF (ms2)
LF/HF (ms2)
SD1 (ms)
SD2 (ms)
SD1/SD2

HRV indexes including SDNN, RMSSD, HF, SD1, and SD2 of the model group, GTS-21 group, and MLA group were much higher than those of the control group. For SDNN, the value and 95% CI were, respectively, 0.000, 1.359~3.380; 0.000, 1.022~3.043; and 0.000, 1.066~3.087. For RMSSD, they were 0.000, 1.070~4.054; 0.003, 0.559~3.543; and 0.005, 0.439~3.423. For HF, they were 0.006, 3.929~31.683; 0.003, 4.845~32.599; and 0.030, 1.012~8.766. For SD1, they were 0.000, 0752~2.864; 0.003,.0390~2.503; and 0.006, 0.304~2.417. For SD2, they were 0.000, 1.486~4.052; 0.000, 1.151~3.717; and 0.000, 1.271~3.837. There were no differences among the groups in such indexes as TP, VLF, LF, LF/HF, and SD1/SD2. SDNN: the standard deviation of all NN intervals; RMSSD: the root mean square successive difference; TP: total power; VLF: very low-frequency; LF: low frequency; HF: high frequency; SD1: standard deviation of width of a scatterplot of successive pairs of RR intervals; SD2: standard deviation of length of a scatterplot of successive pairs of RR intervals. vs. control group.