IL-33 Inhibits Hepatitis B Virus through Its Receptor ST2 in Hydrodynamic HBV Mouse Model

Figure 4

IL-33 can reduce the concentration of HBsAg, but has no significant effect on HBV DNA in C.B-17 SCID HBV mice (a). IL-33 can reduce the concentration of HBsAg and HBV DNA in nod SCID HBV mice after IL-33 treatment (b). IL-33 has no effect on HBeAg in both C.B-17 SCID and nod SCID HBV mice. The statistical significance of the data was determined using the Mann–Whitney test; value is shown in each test.

(a)

(b)