IL-33 Inhibits Hepatitis B Virus through Its Receptor ST2 in Hydrodynamic HBV Mouse Model

Figure 5

Effect of IL-33 on the secretion of HBsAg and HBeAg in the HepG2 cell line transfected with pAAV-HBV 1.2. After treatment with different concentrations of IL-33 (0, 1, and 10 ng/ml) for 24 and 48 hours, HBsAg in the supernatant decreased in a dose-independent manner (a, b); HBeAg in the supernatant significantly decreased in a dose-independent manner (c, d). The statistical significance of the data was determined using the Mann–Whitney test; value is shown in each test.

(a)

(b)

(c)

(d)