Research Article
Antagonistic Peptides That Specifically Bind to the First and Second Extracellular Loops of CCR5 and Anti-IL-23p19 Antibody Reduce Airway Inflammation by Suppressing the IL-23/Th17 Signaling Pathway
Figure 4
Effects of peptides of CCR5 and anti-IL-23p19 mAb on the expression of IL-23p19, IL-23R, IL-17A, and LTF. (a) IL-23p19, IL-23R, IL-17A, and LTF mRNA levels compared with each other among the 7 groups. (b) Fold change of expression levels of the IL-23p19, IL-23R, IL-17A, and LTF proteins. C: control group; S: sensitization group; M: model group; 23: anti-IL-23p19 group; G: GH group; H: HY group; and 23+H: anti-IL-23p19 with the HY group. Values are the (). compared with the model group. # compared with the anti-IL-23p19+HY group. △ compared with the HY group.
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