Antagonistic Peptides That Specifically Bind to the First and Second Extracellular Loops of CCR5 and Anti-IL-23p19 Antibody Reduce Airway Inflammation by Suppressing the IL-23/Th17 Signaling Pathway

<div>Effects of peptides of CCR5 and anti-IL-23p19 mAb on the relationship between CCR5 and IL-23p19. CCR5 mRNA was analyzed by PCR (a), and CCR5 protein was analyzed by western blotting (b) after the administration of the peptides and/or anti-IL-23p19 to mice. C: control group; S: sensitization group; M: model group; 23: anti-IL-23p19 group; G: GH group; H: HY group; 23+H: anti-IL-23p19 with HY group. 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Mediators of Inflammation

fig6

Figure 6

Figure 6: Antagonistic Peptides That Specifically Bind to the First and Second Extracellular Loops of CCR5 and Anti-IL-23p19 Antibody Reduce Airway Inflammation by Suppressing the IL-23/Th17 Signaling Pathway 

Figure 6 | Antagonistic Peptides That Specifically Bind to the First and Second Extracellular Loops of CCR5 and Anti-IL-23p19 Antibody Reduce Airway Inflammation by Suppressing the IL-23/Th17 Signaling Pathway 