CD4+ T Cell Profile and Activation Response in Sickle Cell Disease Patients with Osteonecrosis
Table 1
Demographic and hematologic profiles for peripheral blood, from the control, SCD, and SCD/ON groups.
Control
SCD
SCD/ON
value
Control vs. SCD
Control vs. SCD/ON
SCD vs. SCD/ON
(%)
19 (44.2)
9 (20.9)
15 (34.9)
Age (y)
31 (18-49)
30 (19-47)
31 (18-55)
Male (%)
52.63
88.88
46.66
WBC (103/mm3)
6.9 (3.5-9.3)
7.4 (4.5-13.3)
9.6 (5.0-13.1)
0.182
0.0008
0.546
Lym (%)
37.1 (9.5-54.5)
40.5 (24.2-57.8)
32.8 (26.2-38.7)
0.443
0.272
0.083
RBC (106/mm3)
5.4 (3.3-7.8)
2.9 (2.5-5.1)
3.7 (2.3-5.5)
0.003
0.002
0.469
Hgb (g/dL)
14.6 (9.2-21.0)
10.9 (8.4-13.5)
11.8 (8.6-16.2)
0.009
0.050
0.289
Hct (%)
44.6 (28.4-69.3)
31.3 (23.2-41.0)
33.3 (18.2-50.8)
0.007
0.002
0.666
MCV (fL)
86.2 (76.7-91.0)
93.6 (79.9-101.4)
91.2 (79.2-117.5)
0.010
0.165
0.228
MCH (pg)
27.3 (18.9-34.4)
32.2 (23.7-37.0)
31.6 (27.4-37.3)
0.035
0.013
0.253
RDW (%)a
13.4 (11.8-17.3)
18.3 (17.0-19.4)
14.5 (11.4-18.0)
<0.0001
0.1007
0.0001
Plat (103/μL)
196.0 (107.0-472.0)
241.0 (68.0-451.0)
257.5 (55.0-532.0)
0.950
0.370
0.931
Results are presented as median (min–max), except where noted otherwise. WBC: white blood cell; Lym: lymphocytes; RBC: red blood cells; Hgb: hemoglobin; Hct: hematocrit; MCV: mean corpuscular volume; MCH: mean corpuscular hemoglobin; RDW: red cell distribution width; and Plat: platelets. Significance values are presented as ,,, and .
