Psychobiotics Regulate the Anxiety Symptoms in Carriers of Allele A of IL-1β Gene: A Randomized, Placebo-Controlled Clinical Trial

Table 3

Descriptive characteristics of study population () according to treatments and IL-1β.

(a)

	POSG	PCG		POSG			PCG			A carrier POSG vs. PCG	Noncarrier POSG vs. PCG
	Baseline	Baseline		A carrier	Noncarrier		A carrier	Noncarrier
				Baseline	Baseline		Baseline	Baseline
Total BUT score			0.133			0.871			0.721	0.605	0.231
BUT GSI score			0.123			0.091			0.925	0.128	0.085
Total SCL-90R score			0.441			0.325			0.374	0.325	0.525
SCL-90R GSI score			0.146			0.565			0.567	0.095	0.525
Hamilton score			0.738			0.025			0.012	0.401	0.217
Age			0.091

(b)

	POSG						PCG
	A carrier			Noncarrier			A carrier			Noncarrier
	Baseline	T1		Baseline	T1		Baseline	T1		Baseline	T1
Total BUT score			0.787			0.565			0.521			0.258
BUT GSI score			0.341			0.566			0.128			0.162
Total SCL-90R score			0.140			0.374			0.296			0.624
SCL-90R GSI score			0.302			0.064			0.652			0.136
Hamilton score			0.001			0.152			0.351			0.363

Results are expressed in . -test was used for all parameters. Significant values are for . POSG: probiotic oral suspension group; PCG: placebo control group; BUT: Body Uneasiness Test; SCL90R: Symptom Checklist-Revised; HAM-A: Hamilton Anxiety Rating Scale; BUT GSI: Body Uneasiness Test Global Severity Index; SCL90R GSI: Symptom Checklist-Revised Global Severity Index.