Research Article

Psychobiotics Regulate the Anxiety Symptoms in Carriers of Allele A of IL-1β Gene: A Randomized, Placebo-Controlled Clinical Trial

Table 5

BUT, SLC-90R, and HAM-A frequencies.

BUTSCL-90HAM-A
HealthyDysmorphic symptomsHealthyDepressive symptomsHealthyAnxiety symptoms

A carrierTotal populationT054.55%45.45%68.18%31.82%56.76%43.24%
T161.54%38.46%66.67%33.33%70.97%29.03%
Δ%-6.99%1.52%-14.21%
PCGT0100.00%0.00%100.00%0.00%37.50%62.50%
T1100.00%0.00%100.00%0.00%50.00%50.00%
Δ%0.00%0.00%-12.50%
POSGT047.37%52.63%63.16%36.84%62.07%37.93%
T158.33%41.67%63.64%36.36%78.26%21.74%
Δ%-10.96%-0.48%-16.19%

NoncarrierTotal populationT075.00%25.00%85.00%15.00%88.57%11.43%
T188.89%11.11%87.50%12.50%93.10%6.90%
Δ%-13.89%-2.50%-4.53%
PCGT0100.00%0.00%100.00%0.00%100.00%0.00%
T1100.00%0.00%100.00%0.00%100.00%0.00%
Δ%0.00%0.00%0.00%
POSGT070.59%29.41%82.35%17.65%86.21%13.79%
T183.33%16.67%80.00%20.00%91.30%8.70%
Δ%-12.75%2.35%-5.10%

TotalTotal populationT064.29%35.71%76.19%23.81%72.22%27.78%
T164.29%35.71%76.19%23.81%81.67%18.33%
Δ%0.00%0.00%-9.44%
PCGT0100.00%0.00%100.00%0.00%64.29%35.71%
T1100.00%0.00%100.00%0.00%71.43%28.57%
Δ%0.00%0.00%-7.14%
POSGT058.33%41.67%72.22%27.78%74.14%25.86%
T166.67%33.33%68.75%31.25%84.78%15.22%
Δ%-8.33%3.47%-10.64%

Frequencies for positive/negative classification on depression, dysmorphic, and anxiety symptoms evaluated with Body Uneasiness Test (BUT), Symptom Checklist-Revised (SCL90R), and Hamilton Anxiety Rating Scale (HAM-A). Results are expressed as percentage. POSG: psychobiotic oral suspension group; PCG: placebo control group.