Perspectives in HPV Secondary Screening and Personalized Therapy Basing on Our Understanding of HPV-Related Carcinogenesis Pathways

Table 2

Genotype of HPV and related effect.

HPV genotype	Effect
1, 2, 3, 4, 7, 10, 41	Benign skin lesions—mainly warts
6, 11	Low oncologic risk genotypes; LR HPV; condylomata acuminata—genital warts; slow progression of changes and recurrence of changes are observed
16, 18, 31, 33, 35, 39, 45, 51, 52, 56, 58, 59, 68, 73, 82	High oncologic risk genotypes; HR HPV; play a crucial role in pathogenesis of SIL and anogenital region cancers
5, 8, 14	Cause benign lesions in the type of epidermodysplasia verruciformis

Abbreviations: LR HPV: low-risk human papilloma virus; SIL: squamous intraepithelial lesions; HR HPV: high-risk human papilloma virus.