Research Article

Triticum vulgare Extract Modulates Protein-Kinase B and Matrix Metalloproteinases 9 Protein Expression in BV-2 Cells: Bioactivity on Inflammatory Pathway Associated with Molecular Mechanism Wound Healing

Table 1

In silico analyses reported the characteristics of papers which compare the expression of the MMP9 and p65 proteins included in these analyses. The results were reported in Figure 3(a) through a heat map.

ID paperReferenceMolecules analyzedProinflammatory action with respect to controlAnti-inflammatory action with respect to controlMarkersPathologyCompound
RNAsProteins

125-XYYMMP9, TNF-α, IL-1β, otherBrain injuryOxygen
226XXYYMMP9, TNF-α, IL-1β, IL-6, p65Colon cancermiR-139
327-XNYMMP9, IL-6, otherBrest cancerIlamycin C
428-XYYMMP9, IL-1βInflammatory mechanismmiR-100
529X-NYMMP9, IL-1β, IL-6Inflammatory mechanismNG-NAR
630XXYNMMP9, p65, otherNeck cancerOro-A
731X-NYp65Inflammatory mechanismOlive oil
832XXYYMMP9, TNF-α, IL-6, p65, otherInflammatory mechanismFimA
933XXYYMMP9, AKT, p65, otherBrain injuryGalangin
1034XXYYMMP9, TNF-α, IL-6, p65, otherInflammatory mechanismANGPTL-8
1135XXYYMMP9, p65, otherInflammatory mechanismmiR-145
1236XXYYMMP9, IL-6, p65, otherNeck cancermiR-21
1337XXYYMMP9, IL-6, p65, otherOsteosarcomaIL-6

X:done; -: not done; Y: yes; N: no.