Inflammatory-Related Clinical and Metabolic Outcomes in COVID-19 Patients
Table 2
Association between IL-6 levels, clinical, anthropometrical, and biochemical determinants.
Group 1 ,
Group 2 IL-6 10-100 pg/ml,
Group ,
Chi2/ANOVA
Hypertension
26 (42.3)
25 (45.4)
15 (27.3)
5.61
0.06
Dyslipidemia
23 (41.8)
15 (27.3)
15 (27.3)
3.55
0.17
Diabetes mellitus
15 (27.3)
11 (20.0)
7 (12.7)
3.64
0.16
Charlson Comorbidity Index Score
1.33 (1.66)
0.55 (1.02)
0.64(1.38)
12.68
0.006
ALT (U/l)
47.1 (20.1)
40.8 (22.9)
49.2 (43.0)
57.39
0.01
AST (U/l)
32.0 (15.0)
53.9 (22.8)
52.3 (43.2)
37.93
0.48
GGT (U/l)
71.4 (76.7)
109.9 (121.1)
79.2 (79.7)
15.42
0.08
LDH (U/l)
350.1 (117.6)
388.5 (149.0)
335.3 (157.0)
4.17
0.14
CRP (mg/dl)
182.1 (217.8)
127.9 (70.7)
88.2 (72.2)
90.67
0.02
Leucocytes (counts/μl)
7763 (4026)
7849.4 (3075)
7304 (3553)
3.76
0.69
NLI
10.9 (10.6)
7.2 (5.4)
5.6 (5.3)
34.56
0.001
RDW (%)
13.6 (1.3)
13.2 (1.2)
13.0 (0.9)
5.96
0.02
D-Dimer (μg/ml)
1.60 (2.11)
2.40 (9.01)
1.05 (0.96)
205.80
0.44
Ferritin (ng/ml)
1283(953)
1096 (874)
806 (877)
0.41
0.05
Total cholesterol (mg/dl)
135.3 (33.2)
139.5 (25.2)
145.6 (36.6)
7.60
0.20
SBP (mmHg)
139.2 (24.2)
138.1(21.3)
136.2 (20.3)
1.82
0.78
DBP (mmHg)
78.6 (14.4)
79.4 (12.8)
79.2 (15.3)
1.73
0.94
Baseline blood glucose (mg/dl)
148.1 (77.0)
118.9(44.3)
120.9 (41.2)
24.49
0.01
BMI (kg/m2)
28.8 (4.5)
29.0 (5.0)
27.2 (3.9)
2.60
0.09
Current smoker
7 (12.7)
3 (5.4)
1 (1.8)
5.91
0.05
Drink standard units
8.76 (39.94)
1.74 (4.40)
0.78 (2.47)
1.87
0.15
NLI 2019
2.0 (3.5)
2.8 (4.2)
1.7 (0.8)
59.75
0.28
Hospital stay days
22.0 (17.1)
11.9 (10.4)
8.6 (5.8)
18.04
<0.001
ICU admission
16 (29.1)
4 (7.2)
2 (3.6)
18.04
<0.001
Mortality
13 (23.6)
3 (5.4)
0 (0.0)
20.67
<0.001
ALT: alanine aminotransferase; AST: aspartate aminotransferase; GGT: Gamma Glutamyl Transpeptidase; LDH: lactate dehydrogenase; CRP: C-reactive Protein; NLI: Neutrophil/Lymphocyte index; RDW: Red Cell Distribution Width; SBP: Systolic Blood Pressure; DBP: Diastolic Blood Pressure; BMI: Body Mass Index. Qualitative variables are expressed in number and proportion. Quantitative variables are expressed in mean and standard deviation.
