CD19⁺CD24^hiCD38^hi B Cell Dysfunction in Primary Biliary Cholangitis

Table 1

Clinical features and biochemical parameters of the PBC patients enrolled in this study.

	PBC	HC
Case	38	38
Gender (male/female)	10/28	10/28
Age (years)
AMA (positive/negative)	38/0	—
AMA-M2 (positive/negative)	38/0	—
ALP (U/L)
ALT (U/L)
AST (U/L)
ADA (U/L)
GGT (U/L)
TBIL (μmol/L)
DBIL (μmol/L)
TBA (μmol/L)
IgM (g/L)
Clinical stage
Noncirrhotic stage ()	21	—
Cirrhotic stage ()	12	—
Decompensated cirrhotic stage ()	5	—

Age is expressed as the ; other data are expressed as the median and range. PBC: primary biliary cholangitis; HC: healthy controls. Normal values: ALT, 7-40 U/L; AST, 13-35 U/L; ADA, 0-25 U/L; GGT, 7-45 U/L; ALP, 50-135 U/L; TBIL, 2.1-22.3 μmol/L; DBIL, 0-6.5 μmol/L; TBA, 0-10 μmol/L.