Transforming Growth Factor Beta Receptor 3 Haplotypes in Sickle Cell Disease Are Associated with Lipid Profile and Clinical Manifestations

Figure 1

Linkage disequilibrium analysis of rs2765888 (), rs284875 (), rs2038931 (), rs7526590 (), rs284157 (), and rs1805110 () using the four-gamete rule method. (a) According to HaploView 4.2 color schemes, white corresponds to and , shades of pink/red indicate and , and light blue indicates complete LD with and . (b) Identified haplotypes and associated frequencies. LOD: Log of odds ratio, a measure of confidence of the value of .