Transforming Growth Factor Beta Receptor 3 Haplotypes in Sickle Cell Disease Are Associated with Lipid Profile and Clinical Manifestations

Figure 3

Associations between the GG haplotype and laboratory parameters in individuals with SCD. Carriers of the GG haplotype presented increased (a) total cholesterol (TC) levels, (b) low-density lipoproteins cholesterol (LDL-C) levels, (c) triglycerides, and (d) nonlow-density lipoprotein cholesterol (non-HDL-C) (all values obtained by the Mann-Whitney test). Carriers of the GG haplotype also had presented increased (e) total protein levels ( value obtained with -testing) and (f) increased globulin levels ( value obtained by the Mann-Whitney test).

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