Resolution of Inflammation in Neurodegenerative Diseases: The Role of Resolvins

Figure 4

RvE1 blocks NF-κB and TNFα-signaling pathways through binding to ChemR23 (chemerin 23) receptor, induces apoptosis, and decreases migration. AKT: protein kinase B; ERK: extracellular signal-regulated kinases; RvE1: resolvin E1.