MitoQ Modulates Lipopolysaccharide-Induced Intestinal Barrier Dysfunction via Regulating Nrf2 Signaling

<div>MitoQ alleviates LPS-induced oxidative stress via Nrf2 signaling. (a) qPCR analysis of total Nrf2, GCLM, NQO-1, and HO-1 among four groups. Immunofluorescence staining showing changes in Nrf2 fluorescence (b). MitoQ increases nuclear translocation of Nrf2 (endogenous) in LPS-treated IEC-6 cells.</div>

Mediators of Inflammation

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Figure 6

Figure 6: MitoQ Modulates Lipopolysaccharide-Induced Intestinal Barrier Dysfunction via Regulating Nrf2 Signaling 