Soluble Intercellular Adhesion Molecule- (sICAM-) 1, Thrombospondin-1, and Vinculin for the Identification of Septic Shock Patients Suffering from an Invasive Fungal Infection

Figure 5

ROC analyses for combined measurements of MR-proADM and sICAM-1 for the detection of an IFI in patients with septic shock. Receiver operating characteristic (ROC) analyses with MR-proADM and sICAM-1 in all participating patients at septic shock onset (T0), day 1 (T1), day 2 (T2), day 7 (T3), and day 14 (T4) afterwards with regard to the prediction of an invasive fungal infection (IFI) up to day 28. Patients suffering from an invasive fungal infection (IFI) represented the target group, whereas both patients with a fungal colonization and patients without any fungal isolates served as controls for this ROC analysis. Abbreviations: AUC: area under the curve; CI: confidence interval.