Research Article

Reevaluation of Lung Injury in TNF-Induced Shock: The Role of the Acid Sphingomyelinase

Table 1

Blood gas results.

WT shamWT+TNFWT+zVAD/TNFASM-/- shamASM-/-+TNFASM-/-+zVAD/TNF

pO2/FiO2 (cmH2O)
pCO2 (cmH2O)
pH##
Hb (g/dL)

Blood gas analyses from arterial blood after 405 min of mechanical ventilation with . Data are shown as . Data from mice that died during the experiment were excluded. #, sham-treated groups compared to TNF- and zVAD/TNF-treated groups; compared to WT sham and compared to ASM-/-+TNF; compared to ASM-/-+zVAD/TNF.