Mediators of Inflammation / 2020 / Article / Fig 1

Research Article

Serum Cystatin C and Coronavirus Disease 2019: A Potential Inflammatory Biomarker in Predicting Critical Illness and Mortality for Adult Patients

Figure 1

The nonlinear relationship between baseline ln-transformed cystatin C levels and the prevalence of critical illness (a) and mortality (b) in all COVID-19 patients. The generalized additive model was used for presenting the smoothing splines, adjusted for age, sex, blood creatinine levels, APACHE II scores, and coexistent conditions (such as chronic pulmonary disease, hypertension, diabetes, cardiovascular disease, cerebrovascular disease, and chronic kidney disease). The red lines suggested the risks of critical illness (a) and mortality (b), respectively. The blue dot lines suggested 95% confidence intervals.

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