The Influence of Adalimumab and Cyclosporine A on the Expression Profile of the Genes Related to TGFβ Signaling Pathways in Keratinocyte Cells Treated with Lipopolysaccharide A

Table 4

Changes in the level of selected proteins in cell culture exposed to LPS, LPS+adalimumab, LP+cyclosporine A, and a control culture.

Protein	Control	LPS	LPS+adalimumab			LPS+cyclosporine A
	H-0	H-8	H-2	H-8	H-24	H-2	H-8	H-24
TGFβ1 (pg/ml)	396.85	1159.33	741.04	455.01	211.06	799.14	521.11	341.06
TGFβ2 (pg/ml)	32.85	211.09	110.65	77.01	36.84	144.09	100.27	42.11
JAK2 (ng/ml)	2.22	27.11	12.44	8.01	3.12	11.02	6.37	3.18
BMP2 (pg/ml)	52.09	74.04	369.88	2104.44	2096.58	758.95	1985.09	2145.01
BMP6 (pg/ml)	36411.43	411.08	8856.02	10651.55	13751.06	2214.08	4648.12	10258.09
EDN1 (pg/ml)	12.67	33.25	22.47	21.01	18.25	19.24	18.78	18.96