Mediators of Inflammation

Research Article

Higher Levels of High-Sensitivity C-Reactive Protein Is Positively Associated with the Incidence of Hyperuricemia in Chinese Population: A Report from the China Health and Retirement Longitudinal Study

Table 3

Association between high-sensitivity CRP (mg/L) and change in uric acid concentrations (mg/dL)^a.


	Tertiles of high-sensitivity CRP (mg/L)			β	Standard error	value	^b
	Tertile 1 ()	Tertile 2 ()	Tertile 3 ()	β	Standard error	value	^b

Crude model	0.56 (0.51, 0.60)^c	0.59 (0.55, 0.64)	0.63 (0.58, 0.67)	0.035	0.017	2.09	0.04
Adjusted model 1^d	0.58 (0.53, 0.62)	0.59 (0.54, 0.64)	0.61 (0.56, 0.65)	0.015	0.017	0.90	0.37
Adjusted model 2^e	0.55 (0.50, 0.59)	0.59 (0.55, 0.64)	0.63 (0.59, 0.68)	0.044	0.017	2.61	<0.01

^aCRP: C-reactive protein; BMI: body mass index; HDL: high-density lipoprotein; eGFR: estimate glomerular filtration rate. ^bAnalysis of multiple linear regression. ^cLeast square mean (95% confidence interval) (all such values); analysis of covariance; change in uric acid concentrations (mg/dL) was calculated using data in 2015 minus data in 2011. ^dAdjusted for age, sex, BMI. ^eAdditionally adjusted for education level, smoking status, drinking status, level of income, marital status, fasting blood glucose levels, living area, baseline uric acid, hypertension, total cholesterol, triglycerides, HDL cholesterol, and eGFR based on model 1.