Mediators of Inflammation / 2020 / Article / Tab 4

Research Article

The Change of Systemic Immune-Inflammation Index Independently Predicts Survival of Colorectal Cancer Patients after Curative Resection

Table 4

Univariable and multivariable analysis for disease-free survival.

VariablesUnivariable analysisMultivariable analysis
HR95% CIHR95% CI

Age (≤60/>60, years)1.1000.682-1.7730.696
Gender (male/female)1.3420.850-2.1190.207
KPS (>80/≤80)0.7850.477-1.2930.343
Smoking status (yes/no)1.4010.832-2.3610.205
Localization (rectum/colon)0.8240.515-1.3180.420
Surgical approach (laparoscopy/open)0.9290.588-1.4700.754
Adjuvant therapy (no/yes)0.6270.395-0.9930.0470.4150.250-0.6870.001
CEA (≤5/>5, ng/ml)0.8180.514-1.3020.396
Pathological stage (I–II/III–IV)0.5120.321-0.8140.005
Differentiated degree (high-middle/minor)0.6240.349-1.1180.113
Lymphatic invasion (yes/no)1.5830.994-2.5210.053
Vascular invasion (yes/no)3.5722.118-6.024<0.0013.3051.944-5.620<0.001
ΔSII (>127.7/≤127.7)4.0412.514-6.496<0.0014.9242.992-8.102<0.001

KPS: ∆SII: the change in the systemic immune-inflammation index; KPS: Karnofsky Performance Status; CEA: carcinoembryonic antigen.

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