Regulation of Cyclooxygenase 2 by Filifactor alocis in Fibroblastic and Monocytic Cells

Figure 4

COX2 gene expression in response to F. alocis (OD₆₆₀: 0.1) in the presence and absence of anti-TLR2 blocking antibody in HGF-1 (a) and THP-1 (b) cells at 1 d, as analyzed by qPCR. (). Significant () difference between groups. COX2 gene expression in response to F. alocis (OD₆₆₀: 0.1) in the presence and absence of specific inhibitors against MEK1/MEK2 (U0126; 10 μM), p38 (SB203580; 10 μM), NF-κB (PDTC; 10 μM), and JNK (SP600125; 10 μM) in HGF-1 (c) and THP-1 (d) cells at 1 d, as analyzed by qPCR. (). Significant () difference between groups.

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