Mast Cell Activation, Neuroinflammation, and Tight Junction Protein Derangement in Acute Traumatic Brain Injury

Figure 5

Acute TBI increases VEGFR2 expression in the brain. VEGFR2 expression was analyzed in the frozen sections (20 μm) cut from the brains after 24 h and 72 h of weight drop model of TBI and sham control mouse brains without TBI ( mice/group) by immunofluorescence staining. Representative images and immunoreactivity intensity bar graphs show increased VEGFR2 expression (red color) in 24 h and 72 h acute TBI brains as compared with sham control brains without TBI (, sham control vs. TBI). The nuclei were stained with DAPI (blue color). Photomicrograph original magnifications = 630x.

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