CD137 Signaling Promotes Endothelial Apoptosis by Inhibiting Nrf2 Pathway, and Upregulating NF-<i>κ</i>B Pathway

<div>The role of ROS in endothelial cells apoptosis induced by CD137 signaling. (a) Flow cytometry evaluated ROS production by endothelial cells treated with Asatone or/and CAPE. (b) Western blot analysis tested the expression of p-NF-<i>κ</i>B. (c) Apoptosis of ECs was detected by Annexin V/PI double-staining Flow cytometry. (d) Schematic figure of mechanism. 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Mediators of Inflammation

fig7

Figure 7

Figure 7: CD137 Signaling Promotes Endothelial Apoptosis by Inhibiting Nrf2 Pathway, and Upregulating NF-<i>κ</i>B Pathway 

Mediators of Inflammation

CD137 Signaling Promotes Endothelial Apoptosis by Inhibiting Nrf2 Pathway, and Upregulating NF-κB Pathway

Figure 7