Research Article

IL-4 Receptor-Alpha Signalling of Intestinal Epithelial Cells, Smooth Muscle Cells, and Macrophages Plays a Redundant Role in Oxazolone Colitis

Table 1

Disease activity index scoring sheet (animal distress score).

Appearance
 Normal0
 General lack of grooming1
 Staring coat, ocular and nasal discharges2
 Piloerection, hunched up3
Clinical signs
 Normal color and movement0
 Slight changes in activity1
 Moderate changes: weight loss, diarrhea2
 Severe changes: immobility, lameness3
Natural behavior
 Normal0
 Minor changes1
 Less mobile and alert, isolated2
 Vocalization, restlessness, very still3
Provoked behaviour
 Normal0
 Minor depression or exaggerated response1
 Moderate change in expected behaviour2
 Reacts violently or very weak3

If 3 was scored more than once, an extra point was scored for every 3. .