Global Transcriptional Profiling Reveals Novel Autocrine Functions of Interleukin 6 in Human Vascular Endothelial Cells

<div>Functions regulated by IL6 knockdown in human endothelial cells. Using Ingenuity Pathway Analysis (IPA), diseases and biofunctions regulated by IL6 knockdown in human endothelial cells were evaluated. Diseases and biofunctions were classified into different categories based on the Ingenuity Knowledge Base classification. Activated diseases or biofunctions are indicated in orange, and inhibited diseases or biofunctions are indicated in blue. Categories which include 3 or more functions are shown. 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Mediators of Inflammation

fig7

Figure 7

Figure 7: Global Transcriptional Profiling Reveals Novel Autocrine Functions of Interleukin 6 in Human Vascular Endothelial Cells 