Neutrophil to Lymphocyte Ratio Predicts Adverse Cardiovascular Outcome in Peritoneal Dialysis Patients Younger than 60 Years Old
Table 1
Baseline characteristics of the study population.
Total ()
Group1 ()
Group2 ()
Group3 ()
value
No. of C1/C2/C3/C4
313/794/36/359
123/249/9/120
125/247/7/123
65/298/20/116
<0.001
No. of men/women
852/650
261/240
270/232
321/178
<0.001
NLR
3.3 (2.5, 4.5)
2.2 (1.8, 2.5)
3.3 (3.0, 3.6)
5.4 (4.5, 7.0)
<0.001
Demographics
Age (y)
51.0 (41.0, 62.0)
49.0 (39.0, 61.0)
50.5 (41.0, 61.0)
53.0 (43.0, 63.0)
0.008
BMI (kg/m2)
22.1 (20.1,24.2)
22.1 (20.0, 24.2)
22.1 (20.3, 24.4)
22.1 (20.1, 24.2)
0.400
Comorbid
Systolic BP (mmHg)
146.0 (132.0, 164.0)
146.0 130.0, 160.0)
146.0 (134.0, 161.0)
149.0 (134.0, 170.0)
<0.001
Diastolic BP (mmHg)
86.0 (78.0, 95.0)
86.0 (78.0, 95.0)
86.0 (79.0, 95.0)
86.0 (78.0, 96.0)
0.537
Hypertension
985 (65.6%)
310 (61.9%)
319 (63.5%)
356 (71.3%)
0.004
Diabetes mellitus
343 (22.8%)
106 (21.2%)
115 (22.9%)
122 (24.4%)
0.463
Cardiovascular disease
232 (15.4%)
68 (13.6%)
77 (15.3%)
87 (17.4%)
0.239
Treatments
CCB
1104 (73.5%)
369 (73.7%)
367 (73.1%)
368 (73.7%)
0.970
Loop diuretic
100 (6.7%)
32 (6.4%)
30 (6.0%)
38 (7.6%)
0.557
Insulin
231 (15.4%)
75 (15.0%)
71 (14.1%)
85 (17.0%)
0.427
Laboratory variables
WBC (109/L)
6.1 (4.9, 7.6)
5.3 (4.3, 6.6)
6.1 (5.0, 7.3)
6.9 (5.7, 9.0)
<0.001
Neutrophil (109/L)
4.1 (3.1, 5.2)
3.0 (2.4, 3.8)
4.1 (3.5, 4.8)
5.3 (4.2, 6.9)
<0.001
Lymphocyte (109/L)
1.2 (0.9, 1.6)
1.5 (1.2, 1.9)
1.2 (1.0, 1.5)
0.9 (0.7, 1.2)
<0.001
Hemoglobin (g/L)
87.0 (74.0, 100.0)
89.0 (76.0, 103.0)
87.0 (75.0, 101.0)
83.0 (70.0, 95.0)
<0.001
Albumin (g/L)
34.6 (31.1, 37.9)
34.9 (31.4, 38.4)
34.7 (31.3, 37.4)
34.2 (30.7, 37.6)
0.046
Creatinine (μmol/L)
708.1 (543.8, 931.1)
699.0 (543.5, 898.5)
713.0 (542.0, 932.7)
728.0 (546.0, 948.8)
0.606
Urea nitrogen (mmol/L)
20.5 (15.5, 26.8)
19.5 (15.2, 25.4)
20.2 (15.3, 26.4)
21.8 (16.3, 29.4)
<0.001
Uric acid (mmol/L)
428.0 (356.0, 508.3)
428.0 (356.0, 511.5)
428.0 (355.0, 504.0)
428.0 (360.0, 504.0)
0.891
FBG (mmol/L)
4.7 (4.1, 5.5)
4.6 (4.1, 5.4)
4.7 (4.1, 5.5)
4.8 (4.1, 5.6)
0.033
Cholesterol (mmol/L)
4.2 (3.5, 5.0
4.3 (3.7, 5.0)
4.2 (3.5, 4.9)
4.2 (3.4, 4.9)
0.009
Triglycerides (mmol/L)
1.3 (1.0, 1.8)
1.3 (1.0, 1.8)
1.3 (1.0, 1.8)
1.3 (0.9, 1.7)
0.029
Sodium (mmol/L)
140.1 (138.0, 142.3)
140.6 (138.3, 142.5)
140.0 (138.0, 142.9)
140.0 (137.7, 142.0)
0.017
Chlorine (mmol/L)
103.0 (99.4, 107.0)
103.2 (99.9, 107.0)
103.0 (99.3, 106.8)
102.8 (99.0, 107.0)
0.103
Calcium (mmol/L)
2.0 (1.9, 2.2)
2.1 (1.9, 2.2)
2.0 (1.9, 2.2)
2.0 (1.8, 2.1)
<0.001
Potassium (mmol/L)
4.1 (3.6, 4.7)
4.2 (3.7, 4.8)
4.1 (3.6, 4.7)
4.1 (3.6, 4.7)
0.226
Phosphorus (mmol/L)
1.7 (1.4, 2.0)
1.7 (1.4, 2.0)
1.7 (1.3, 2.0)
1.7 (1.4, 2.1)
0.005
Total
2.2 (1.8, 2.6)
2.2 (1.8, 2.7)
2.2 (1.7, 2.6)
2.2 (1.8, 2.6)
0.099
RRF(mL/min)
3.9 (2.1, 7.2)
3.9 (2.0, 7.6)
3.9 (2.2, 7.1)
3.9 (2.0, 6.8)
0.856
Note: All continuous variables are skewed distribution, the values for continuous variables are given as median (P25, P75). Abbreviations: C1: center 1; C2: center 2; C3: center 3; C4: center 4; NLR: neutrophil lymphocyte ratio; BMI: body mass index; BP: blood pressure; CCB: calcium channel blocker; WBC: white blood cell; FBG: fasting blood glucose; :, dialyzer clearance of urea; , dialysis time; , volume of distribution of urea; RRF: renal residual function.
