Research Article

Neutrophil to Lymphocyte Ratio Predicts Adverse Cardiovascular Outcome in Peritoneal Dialysis Patients Younger than 60 Years Old

Table 3

Relationship between NLR and new-onset CV event as well as CVD mortality.

Tertile 2Tertile 3
HR (95% CI)HR (95% CI)

New-onset CV event
 Unadjusted0.93 (0.65-1.33)0.7011.72 (1.25-2.37)0.001
 Model 10.88 (0.62-1.26)0.4991.41 (1.02-1.95)0.037
 Model 20.88 (0.62-1.26)0.4831.39 (1.01-1.93)0.046
 Model 30.88 (0.62-1.26)0.4831.39 (1.01-1.93)0.046
CVD mortality
 Unadjusted1.18 (0.77-1.81)0.4361.98 (1.34-2.93)0.001
 Model 11.17 (0.77-1.79)0.4651.73 (1.17-2.56)0.007
 Model 21.16 (0.76-1.78)0.4951.74 (1.17-2.57)0.006
 Model 31.19 (0.78-1.82)0.4161.81 (1.22-2.69)0.003

Note: reference group is the low NLR group. Model 1: sex, age, and BMI. Model 2: new-onset CV event: Model 1 plus medical history (diabetes mellitus, hypertension). CVD mortality: Model 1 plus medical history (diabetes mellitus, hypertension, and CVD). Model 3: Model 2 plus albumin, creatinine, urea nitrogen, triglycerides, cholesterol, chlorine, phosphorus, , and RRF. Abbreviations: NLR: neutrophil lymphocyte ratio; HR: hazard ratio; CI: confidence interval; CVD: cardiovascular disease; BMI: body mass index; : , dialyzer clearance of urea; , dialysis time; , volume of distribution of urea; RRF: residual renal function.