Relationship of Serum Levels of IL-17, IL-18, TNF-α, and Lung Function Parameters in Patients with COPD, Asthma-COPD Overlap, and Bronchial Asthma

Table 3

Correlations between the serum concentration of IL-17 and the lung function parameters in patients with COPD, asthma-COPD overlap, and bronchial asthma.

Spirometric indicators	COPD		АСО		BA
	FVC (l)	-0.51	≤0.001	-0.42	0.022	-0.4	0.045
FVC (%)	-0.35	0.02	-0.53	0.002	-0.49	0.03
FEV1 (l)	-0.53	≤0.001	-0.48	0.007	-0.46	0.03
FEV1 (%)	-0.55	≤0.001	-0.268	0.152	-0.27	0.32
FEV1/FVC (%)	-0.62	≤0.001	0.031	0.87	-0.53	0.02
FEF25 (l)	-0.54	≤0.001	-0.24	0.2	-0.13	0.69
FEF25 (%)	-0.53	≤0.001	-0.018	0.32	-0.21	0.28
FEF50 (l)	-0.33	0.043	-0.089	0.64	-0.23	0.21
FEF50 (%)	-0.53	≤0.001	-0.065	0.73	-0.21	0.27
FEF75 (l)	-0.56	≤0.001	-0.205	0.27	0.15	0.65
FEF75 (%)	-0.46	0.002	-0.296	0.11	-0.13	0.7
IC (%)	-0.31	0.049	-0.211	0.26	-0.2	0.35

: correlation coefficient; COPD: chronic obstructive pulmonary disease; ACO: asthma-COPD overlap; BA: bronchial asthma.