Review Article
The Association between Inflammation and Pulse Wave Velocity in Dyslipidemia: An Evidence-Based Review
Table 2
Values of related parameters in each study.
| | Ref. | Subjects | CRP/hs-CRP value | PWV value | SBP/DBP (mmHg) | HR (bpm) | TC | HDL-C | LDL-C | TG |
| | [18] | FH | 0.10 (0.05–0.16) mg/dL | m/s | / | nm | mg/dL | mg/dL | mg/dL | 92 (74.5–110.5) mg/dL | | Non-FH | 0.08 (0.04–0.14) mg/dL | m/s | / | nm | mg/dL | mg/dL | mg/dL | 106 (82.75–129.5) mg/dL | | FH vs. non-FH ( value) | ns | <0.05 | ns | — | ns | ns | ns | ns |
| | [19] | Before diet intervention | 1.8 (0.8–2.7) mg/L | m/s | / | 64 | mmol/L | mmol/L | mmol/L | mmol/L | | After diet intervention | 1.1 (0.4–1.7) mg/L | m/s | / | | mmol/L | mmol/L | mmol/L | mmol/L | | Before vs. after intervention ( value) | 0.001 | 0.02 | ns | ns | 0.008 | ns | 0.02 | ns |
| | [20] | HC subjects | 1.65 (0.7–2.9) mg/L | m/s | / | | mmol/L | mmol/L | mmol/L | mmol/L | | Control subjects | 0.70 (0.3–1.7) mg/L | m/s | / | | mmol/L | mmol/L | mmol/L | mmol/L | | HC vs. control ( value) | 0.03 | <0.001 | ns | 0.4 | <0.001 | 0.8 | <0.001 | 0.3 |
| | [21] | FH | 1.7 (0.2–34) mg/L | m/s | / | nm | mg/dL | mg/dL | mg/dL | mg/dL | | NL | 1.3 (0.2–8) mg/L | m/s | / | nm | mg/dL | mg/dL | mg/dL | mg/dL | | FH vs. NL ( value) | ns | 0.007 | ns | | <0.001 | ns | <0.001 | <0.001 |
| | [22] | Group A | Before tx | 2.86 (1.87-6.87) mg/L | cm/s | / | | nm | mg/dL | mg/dL | 139 (119-258) mg/dL | | After tx | 0.46 (0.29-1.87) mg/L | cm/s | / | | nm | mg/dL | mg/dL | 121 (84- 167) mg/dL | | Before tx vs. after tx ( value) | <0.001 | <0.01 | ns | ns | — | <0.05 | <0.001 | <0.05 | | Group B | Before tx | 2.69 (1.69-7.09) mg/L | cm/s | / | | nm | mg/dL | mg/dL | 141 (115-279) mg/dL | | After tx | 0.44 (0.25-1.71) mg/L | cm/s | / | | nm | mg/dL | mg/dL | 122 (88-175) mg/dL | | Before tx vs. after tx ( value). | <0.001 | <0.05 | ns | ns | — | ns | <0.01 | <0.05 |
| | [23] | Group A | Before tx | mg/L | cm/s | / | | mg/dL | mg/dL | mg/dL | mg/dL | | After tx | mg/L | cm/s | / | | mg/dL | mg/dL | mg/dL | mg/dL | | Before tx vs. after tx ( value) | ns | <0.05 | ns | ns | <0.05 | ns | <0.05 | <0.05 | | Group B | Before tx | mg/L | cm/s | / | | mg/dL | mg/dL | mg/dL | mg/dL | | After tx | mg/L | cm/s | / | | mg/dL | mg/dL | mg/dL | mg/dL | | Before tx vs. after tx ( value) | <0.05 vs. final tx group A | <0.05 vs. before tx.
<0.05 vs. final tx group A | For SBP:
<0.05 vs. before tx.
<0.05 vs. final tx group A | ns | <0.05 | ns | <0.05 | <0.05 |
| | [24] | FH | mg/L | cm/s |
| nm | mg/dL | mg/dL | mg/dL | mg/dL | | Control | mg/L | cm/s | / | nm | mg/dL | mg/dL | mg/dL | mg/dL | | FH vs. control ( value) | ns | ns | ns | nm | <0.001 | ns | <0.001 | ns |
| | [25] | Men | mg/dL | cm/s | / | | mmol/L | mmol/L | mmol/L | mmol/L | | Women | mg/dL | cm/s | / | | mmol/L | mmol/L | mmol/L | mmol/L | | Men vs. women ( value) | ns | ns | <0.05 for both | ns | <0.05 | ns | ns | <0.05 |
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Abbreviation: CRP: C-reactive protein; FH: familial hypercholesterolemia; HC: hypercholesterolaemic; HDL-C: high-density lipoprotein cholesterol; hs-CRP: high-sensitivity C-reactive protein; LDL-C: low-density lipoprotein cholesterol; NL: normolipidemia; nm: not mentioned; ns: not significant; PWV: pulse wave velocity; SBP: systolic blood pressure; TC: total cholesterol; TG: triglyceride; tx: treatment.
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