Analysis of Myocardial Ischemia Parameters after Coronary Artery Bypass Grafting with Minimal Extracorporeal Circulation and a Novel Microplegia versus Off-Pump Coronary Artery Bypass Grafting
Table 4
Cardiac markers.
Crude nonparametric analysis, before IPTW
Adjusted, after IPTW
OPCAB ()
Microplegia ()
OPCAB ()
Microplegia ()
Effect on median
hs-cTnT, POD1 in ng/L, median (IQR)
176 (106-258)
225 (159-372)
<0.001
174 (73-274)
213 (117-308)
39 (-8-87)
0.105
Peak hs-cTnT in ng/L, median (IQR)
187 (112-318)
237 (167-380)
0.001
178 (68-289)
213 (109-318)
35 (-13-84)
0.155
CK-MB POD1 in μg/L, median (IQR)
8.6 (5.3-13.9)
13.4 (9.3-19.7)
<0.001
6.7 (1.3-12.1)
11.6 (6.7-16.4)
4.9 (2.3-7.4)
0.000
Peak CK-MB in μg/L, median (IQR)
9.4 (5.6-14.6)
13.4 (9.3-19.9)
<0.001
8.0 (2.7-13.4)
12.0 (7.2-16.8)
4.0 (1.4-6.5)
0.002
CK POD1 in U/L, median (IQR)
357 (233-542)
503 (322-691)
<0.001
174 (0-376)
295 (113-478)
121 (27-216)
0.012
Peak CK in U/L, median (IQR)
508 (339-783)
577 (401-768)
0.296
404 (166-642)
371 (156-585)
-34 (-137-70)
0.522
Note that average cardiac markers on the right hand side are estimated from median regression at the average of the covariates (main stem stenosis, use of BIMA, duration of operation, and number of distal anastomoses) after IPTW. Data are presented as median with an interquartile range. OPCAB: off-pump coronary artery bypass grafting; hs-cTnT: high-sensitivity cardiac troponin T; CK: creatine kinase; CK-MB: creatine kinase-myocardial type; POD: postoperative day; IPTW: inverse probability of treatment weighting.
