The Effects of Dietary Glycine on the Acetic Acid-Induced Mouse Model of Colitis

Figure 4

Intestinal microbiota. (a) Two hundred thirty-three OTUs were common to all three groups. (b) Relative contribution of genera in each group. (c) Prominent populations in each: Clostridia and Clostridiales in the Con group, Alcaligenaceae, Burkholderiales, and Betaproteobacteria in the Mod group, and Ruminococcaceae in the ModGly group. (d) The correlation analysis showed that serum concentrations of valine and leucine were negatively correlated with the abundance of Clostridia and Clostridiales (e); IL-10 expression was positively correlated with the abundance of Clostridia, Clostridiales, and IL-1 expression was negatively correlated with the abundance of Ruminococcaceae.

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