Research Article

Age-Related Differences in the Association between Plasma High-Sensitivity C-Reactive Protein and Noncalcified or Mixed Coronary Atherosclerotic Plaques

Table 3

Demographic and clinical characteristics of the study subjects according to age-specific tertiles of hsCRP.

Variables
<1.02 ()1.02-2.37 ()>2.37 ()<1.25 ()1.25–2.70 ()>2.70 ()

Age (years)0.8910.058
BMI (kg/m2)<0.0010.617
Male, (%)111 (63.1%)111 (63.1%)120 (68.6%)0.46076 (53.9%)56 (39.4%)62 (44.0%)0.044
Hypertension, (%)92 (52.3%)117 (66.5%)118 (67.4%)0.005102 (72.3%)102 (71.8%)115 (81.6%)0.103
Diabetes, (%)25 (14.2%)35 (19.9%)42 (24.0%)0.06639 (27.7%)46 (32.4%)37 (26.2%)0.488
Dyslipidemia, (%)108 (61.4%)122 (69.3%)117 (66.9%)0.273113 (80.1%)107 (75.4%)109 (77.3%)0.624
TC (mmol/L)0.0560.041
TG (mmol/L)1.41 (0.96, 2.11)1.67 (1.31, 2.41)1.64 (1.09, 2.49)0.1181.28 (0.95, 1.64)1.51 (1.12, 2.15)1.41 (1.00, 2.06)0.380
LDL-C (mmol/L)0.0910.011
HDL-C (mmol/L)<0.0010.001
CCTA data, (%)
 CR54 (30.7%)61 (11.6%)46 (26.3%)0.23411 (7.8%)18 (12.7%)9 (6.4%)0.151
 CP53 (30.1%)44 (25.0%)62 (35.4%)0.10492 (65.2%)68 (47.9%)69 (48.9%)0.005
 NCP/MP69 (39.2%)71 (40.3%)67 (38.3%)0.92538 (27.0%)56 (39.4%)63 (44.7%)0.007

Abbreviations: hsCRP—high-sensitivity C-reactive protein; BMI—body mass index; TC—total cholesterol; TG—triglycerides; HDL-C—high-density lipoprotein cholesterol; LDL-C—low-density lipoprotein cholesterol; CCTA—coronary computed tomography angiography; CR—control; CP—calcified plaque; NCP—noncalcified plaque; MP—mixed plaque.