Assessing the Effects of Parthenolide on Inflammation, Bone Loss, and Glial Cells within a Collagen Antibody-Induced Arthritis Mouse Model

Figure 4

Histological assessment of the radiocarpal joint and hind paws: (a) representative haematoxylin and eosin- (H&E-) stained images of the radiocarpal joint (20x magnification; scale bars represent 100 μm). Semiquantitative analysis of inflammatory cell infiltration, cartilage and bone degradation, and pannus formation in H&E-stained sagittal sections of the radiocarpal (b) and hind paws (c). Error bars represent SEM ( paws per control, CAIA+PAR 1 mg/kg, and CAIA+PAR 4 mg/kg, paws per CAIA; and compared to control).

(a)

(b) Radiocarpal joint

(c) Hind paw