Research Article
Serum Soluble Interleukin-2 Receptor Does Not Differentiate Complex Regional Pain Syndrome from Other Pain Conditions in a Tertiary Referral Setting
Table 6
CRPS severity score-Database Form: presence of symptoms and signs of CRPS in each group.
| | Symptoms | No CRPS () | CRPS () | Significance |
| | NRS at time of visit (median, Q3-Q1) | 7.0 (8.0-3.0) | 7.0 (8.0-6.0) | NS | | NRS 24 hours before visit (median, Q3-Q1) | 7.5 (8.0-6.3) | 8.0 (8.0-7.0) | NS | | Continuing pain (, %) | 18 (62.1) | 23 (100) | | | Allodynia and/or hyperalgesia | 27 (93.1) | 23 (100) | NS | | Allodynia | 14 (48.3) | 17 (73.9) | NS | | Hyperalgesia | 24 (82.8) | 23 (100) | NS | | Temperature asymmetry | 27 (93.1) | 20 (87.0) | NS | | Affected side warmer | 11 (37.9) | 7 (30.4) | NS | | Affected side colder | 9 (31.0) | 5 (21.7) | NS | | Affected side warm/cold | 7 (24.1) | 8 (34.8) | NS | | Color asymmetry | 23 (79.3) | 23 (100) | | | Red | 14 (48.3) | 13 (56.5) | NS | | Blue | 5 (17.2) | 8 (34.8) | NS | | Other color | 12 (41.4) | 14 (60.9) | NS | | Sweating asymmetry | 12 (41.4) | 14 (60.9) | NS | | Edema | 24 (82.8) | 21 (91.3) | NS | | Dystrophic changes | 15 (51.7) | 17 (73.9) | NS | | Nails | 10 (34.5) | 12 (52.2) | NS | | Hair | 8 (27.6) | 11 (47.8) | NS | | Skin | 6 (20.7) | 10 (43.5) | NS | | Motor abnormalities | 29 (100) | 23 (100) | N/A | | Weakness | 25 (86.2) | 22 (95.7) | NS | | Tremor | 15 (51.7) | 13 (56.5) | NS | | Dystonia | 13 (44.8) | 10 (43.5) | NS | | Decreased AROM | 20 (69.0) | 22 (95.7) | | | Myoclonus | 4 (13.8) | 9 (39.1) | NS | | Signs | No CRPS () | CRPS () | Significance | | Hyperalgesia to pinprick | 11 (37.9) | 17 (73.9) | | | Allodynia | 18 (62.1) | 22 (95.7) | | | Light touch | 6 (20.7) | 19 (82.6) | | | Deep joint pressure | 9 (31.0) | 18 (78.3) | | | Vibration | 8 (27.6) | 14 (60.9) | | | Cold | 2 (6.9) | 11 (47.8) | | | Heat | 3 (10.3) | 11 (47.8) | | | Temperature asymmetry on palpation | 2 (6.9) | 8 (34.8) | | | Affected side cooler | 1 (3.4) | 8 (34.8) | | | Affected side warmer | 1 (3.4) | 0 | NS | | Color asymmetry | 4 (13.8) | 12 (52.2) | | | Red | 3 (10.3) | 9 (39.1) | | | Blue or pale | 3 (10.3) | 4 (17.4) | NS | | Mottled | 0 | 4 (17.4) | N/A | | Scar | 0 | 0 | N/A | | Sweating asymmetry | 1 (3.4) | 6 (26.1) | | | Increased on affected side | 1 (3.4) | 6 (26.1) | | | Decreased on affected side | 0 | 0 | N/A | | Asymmetric edema | 1 (3.4) | 6 (26.1) | | | Dystrophic changes | 4 (13.8) | 7 (30.4) | NS | | Nails | 1 (3.4) | 5 (21.7) | NS | | Hair | 3 (10.3) | 2 (8.7) | NS | | Skin | 1 (3.4) | 4 (17.4) | NS | | Motor abnormalities affected side | 20 (69.0) | 21 (91.3) | NS | | Tremor or myoclonus | 2 (6.9) | 6 (26.1) | NS | | Dystonia | 2 (6.9) | 7 (30.4) | NS | | Decreased AROM | 16 (55.2) | 17 (73.9) | NS | | Weakness 1/51 | 0 | 3 (13.0) | N/A | | Weakness 2/52 | 0 | 5 (21.7) | N/A | | Weakness 3/53 | 4 (13.8) | 5 (21.7) | NS | | Weakness 4/54 | 12 (41.4) | 7 (30.4) | NS | | CRPS severity score (mean, sd) | 8.1 (1.9) | 11.4 (2.2) | <0.001 |
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1Weakness 1/5: flicker of movement. 2Weakness 2/5: movement with gravity. 3Weakness 3/5: movement against gravity. 4Weakness 4/5: weak. |
