High CD163 Expression on Classical Monocytes Is Associated with Immune Control of HBV Infection in Noncirrhotic Patients

Table 1

Demographic, clinical, and laboratory characteristics of studied CHB groups. N/A: nonapplicable.

	HBV patients	HBsAg/anti-HBs seroconverted	Healthy subjects
Epidemiology
Patients	60	9	15
Gender, m/f (%)	35/25 (58.3/41.7)	6/3 (66.7/33.3)	7/8 (46.7/53.3)
Age, median, range	37, 20-84	57, 23-79	38, 29-61
Laboratory results
ALT (U/L), median, range	26, 11-100	22, 10-42	26, 11-43
AST (U/L), median, range	21, 8-53	N/A	N/A
CRP (mg/L), median, range ( mg/L)	0.8, 0.1-4.0	1.3, 0.6-1.8	0.6, 0.1-1.8
WBC (/nL), median, range	5.62, 3.36-9.0	6.36, 4.48-8.67	6.05, 4.05-7.21
Monocytes (%), median, range	10.0, 6.4-18.5	10.7, 8.5-17.9	9.4, 7.1-11.7
Neutrophils (%), median, range	54.1, 40.7-70.0	53.3, 10.1-65.4	51.8, 43.7-66.6
Lymphocytes (%), median, range	32.0, 18.6-44.3	34.8, 23.2-37.6	34.1, 24.5-42.2
Thrombocytes (/nL), median, range	209, 40-401	192, 101-272	233, 178-306
AST to platelet ratio index (APRI)	0.25, 0.09-1.0	N/A	N/A
HBV-DNA (log10 IU/mL), median, range	2.57, 1.28-7.64	N/A	N/A
qHBsAg (log10 IU/mL), median, range	4.06, 0.95-4.69	N/A	N/A
HBV genotype
A	13 (72.2)	N/A	N/A
A+D	1 (0.6)	N/A	N/A
D	2 (1.2)	N/A	N/A
F	1 (0.6)	N/A	N/A
H	1 (0.6)	N/A	N/A
Histology—necroinflammatory activity grade (Scheuer),
1, (%)	8 (28.6)	N/A	N/A
2, (%)	13 (46.4)	N/A	N/A
3, (%)	7 (25.0)	N/A	N/A
4, (%)	0	N/A	N/A
Histology—fibrosis stage (Scheuer)
1, (%)	21 (75.0)	N/A	N/A
2, (%)	7 (25.0)	N/A	N/A
3, (%)	0	N/A	N/A
4, (%)	0	N/A	N/A