Research Article

Long-Term Effectiveness of Secukinumab in Patients with Axial Spondyloarthritis

Table 1

Demographic and clinical data combined with therapeutic features of patients with axSpA enrolled in our study.

Demographic features

Age (years)
Disease duration (years)
Females/males27/12
Clinical features(%)
HLA B27 +6/39 (15.38%)
Psoriasis19/39 (48.71)%
Radiographic SpA26/39 (66.66%)
Peripheral involvement31/39 (79.48%)
GI tract involvement0/39 (0%)
Ocular involvement4/39 (10.25%)
PPD test +4/39 (10.25%)
QFT +4/39 (10.25%)
Therapeutic features(%)
Previous anti-TNF failure29/39 (74.35%)
Use of concomitant GC11/39 (28.20%)
Use of concomitant DMARDs14/39 (35.89%)
SCK 150/mg/injection17/39 (43.58%)
SCK 300/mg/injection22/39 (56.41%)

GC: glucocorticoids; GI: gastrointestinal; HLA: human leukocyte antigen; PPD: purified protein derivative; QFT: quantiFERON-TB; SCK: secukinumab; SD: standard deviation; SpA: spondyloarthritis; TNF: tumour necrosis factor.