Research Article

Midregional Proadrenomedullin (MRproADM) Serum Levels in Critically Ill Patients Are Associated with Short-Term and Overall Mortality during a Two-Year Follow-Up

Table 5

Uni- and multivariate logistic regression analyses for MRproADM levels at ICU admission to predict ICU and overall mortality.

ParameterICU mortalityOverall mortality
Unadjusted OR (95% CI)Adjusted OR (95% CI)Unadjusted OR (95% CI)Adjusted OR (95% CI)

3.7 (1.47-9.29)0.0053.15 (1.08-9.20)0.0362.8 (1.44-5.55)0.0032.4 (1.12-5.34)0.026
Lactate1.159 (1.01-1.33)0.0401.20 (1.01-144)0.0431.19 (1.02-1.39)0.0271.25 (1.04-1-51)0.016
Age1.04 (1.01-1.06)0.0041.03 (0.99-1-06)n.s.1.04 (1.01-1.06)0.0011.03 (1.00-1-05)n.s.
APACHE II1.09 (1.04-1.14)<0.0011.06 (1.01-1.12)0.0141.06 (1.02-1.10)0.0041.03 (0.99-1-08)n.s.

Abbreviations: 95% CI: 95% confidence interval; APACHE II: acute physiology and chronic health evaluation; MRproADM: midregional proadrenomedullin; OR: odds ratio.