Research Article
Association of C1q/TNF-Related Protein-9 (CTRP9) Level with Obstructive Sleep Apnea in Patients with Coronary Artery Disease
Table 1
Baseline characteristics of subjects with moderate/severe OSA and no/mild OSA.
| | Variables | All () | Moderate/severe OSA () | No/mild OSA () | |
| | Age (years) | | | | 0.619 | | Male (%) | 136 (88.3) | 83 (93.3) | 53 (81.5) | 0.025 | | BMI (kg/m2) | | | | 0.012 | | Waist-to-hip ratio | 0.97 (0.94-1.01) | 0.98 (0.95-1.02) | 0.97 (0.93-1.00) | 0.032 | | Neck circumference (cm) | 40.0 (38-42) | 40.5 (38-42) | 40.0 (37-44) | <0.001 | | Systolic BP (mm/Hg) | 126 (116-139) | 129 (115-140) | 125 (115-136) | 0.389 | | Diastolic BP (mm/Hg) | 76 (70-86) | 79 (70-87) | 74 (70-85) | 0.176 | | Hypertension (%) | 89 (57.8) | 54 (60.7) | 35 (53.8) | 0.397 | | Hyperlipidemia (%) | 38 (24.7) | 23 (25.8) | 15 (23.1) | 0.694 | | Current smoking (%) | 76 (49.4) | 53 (59.6) | 23 (35.4) | 0.015 | | Previous CAD (%) | 49 (31.8) | 29 (32.6) | 20 (30.8) | 0.811 | | Previous myocardial infarction (%) | 19 (12.3) | 12 (13.5) | 7 (10.8) | 0.613 | | Previous PCI (%) | 24 (15.6) | 18 (20.2) | 6 (9.2) | 0.063 | | LDL-cholesterol (mmol/L) | 2.3 (1.8-3.1) | 2.4 (1.9-3.0) | 2.1 (1.7-3.0) | 0.635 | | HDL-cholesterol (mmol/L) | 1.03 (0.89-1.18) | 1.03 (0.91-1.20) | 1.01 (0.89-1.13) | 0.010 | | Total cholesterol (mmol/L) | 3.9 (3.3-5.0) | 4.2 (3.45-4.9) | 3.8 (3.2-4.8) | 0.948 | | Triglyceride (mmol/L) | 1.4 (1.0-2.3) | 1.5 (1.0-2.2) | 1.3 (0.9-2.1) | 0.448 | | LVEF (%) | 60 (55-65) | 62 (60-65) | 55 (48-60) | 0.582 | | CTRP9 (ng/mL) | 4.9 (4.3-5.5) | 4.7 (4.1-5.2) | 4.9 (4.4-6.0) | 0.003 | | hsCRP (mg/L) | 1.5 (0.6-5.1) | 1.2 (0.5-3.3) | 2.0 (0.6-5.9) | 0.103 | | HCY (μmol/L) | 12.7 (9.4-19.1) | 12.7 (9.3-16.0) | 11.9 (9.5-19.2) | 0.618 | | HbA1c (%) | 5.8 (5.4-6.0) | 5.8 (5.5-6.2) | 5.6 (5.4-6.0) | 0.293 | | Fasting glucose (mmol/L) | 5.48 (5.07-5.95) | 5.54 (5.07-6.00) | 5.48 (5.12-5.86) | 0.220 | | AHI (events/h) | 19.1 (9.9-33.5) | 29.0 (21.9-38.8) | 8.5 (4.3-10.9) | <0.001 | | ODI (events/h) | 20.7 (11.7-30.7) | 27.2 (21.2-36.2) | 10.5 (4.6-13.9) | <0.001 | | Minimum SaO2 (%) | 85 (81-89) | 83 (79-87) | 88 (83-90) | <0.001 | | Mean SaO2 (%) | 94 (93-95) | 93 (93-95) | 94 (94-95) | 0.001 | | Time with SaO2 <90% (%) | 3.0 (0.2-8.0) | 5.0 (2.0-14.0) | 0.8 (0-3.3) | <0.001 |
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Data are presented as : median (first quartile: third quartile): or (%). AHI: apnea-hypopnea index; BMI: body mass index; BP: blood pressure; CAD: coronary artery disease; CTRP9: C1q/TNF-related protein 9; HbA1c: glycated hemoglobin; HCY: homocysteine; HDL: high-density lipoprotein; hsCRP: high-sensitivity C-reactive protein; LDL: low-density lipoprotein; LVEF: left ventricular ejection fraction; ODI: oxygen desaturation index; OSA obstructive sleep apnea; PCI: percutaneous coronary intervention; SaO 2: arterial oxygen saturation. |
