The Role of Angiogenesis Factors in the Formation of Vascular Changes in Scleroderma by Assessment of the Concentrations of VEGF and sVEGFR2 in Blood Serum and Tear Fluid
Table 1
Characteristic of analyzed groups.
Feature
Group
SSc ()
lSSc ()
dSSc ()
Control ()
Gender
Female
21
14
7
20
Male
4
3
1
5
Age (years) (±SD)
57.1 (10.8)
60.2 (9.4)
50.6 (11.4)
59.4 (9.9)
Ulcerations
Present
19
13
6
Absent
6
4
2
Raynaud time (years) (±SD)
10.9 (5.7)
11.4 (5.7)
9.9 (6.1)
Gastrointestinal manifestation
15 (60%)
10 (59%)
5 (62%)
Cardiac involvement
17 (68%)
11 (65%)
6 (75%)
Pulmonary fibrosis
11 (44%)
7 (41%)
4 (50%)
Renal abnormalities
4 (16%)
1 (6%)
3 (37%)
Hematological involvement
6 (24%)
4 (23%)
2 (25%)
Arthralgia
19 (76%)
13 (76%)
6 (75%)
Results are shown as number and percent. Duration is presented in years as of the mean. Abbreviations: SSc: scleroderma; lSSc: limited systemic sclerosis; dSSc: diffuse systemic sclerosis; SD: standard deviation.