Research Article

The Role of Angiogenesis Factors in the Formation of Vascular Changes in Scleroderma by Assessment of the Concentrations of VEGF and sVEGFR2 in Blood Serum and Tear Fluid

Table 1

Characteristic of analyzed groups.

FeatureGroup
SSc ()lSSc ()dSSc ()Control ()

Gender
 Female2114720
 Male4315
Age (years) (±SD)57.1 (10.8)60.2 (9.4)50.6 (11.4)59.4 (9.9)
Ulcerations
 Present19136
 Absent642
Raynaud time (years) (±SD)10.9 (5.7)11.4 (5.7)9.9 (6.1)
Gastrointestinal manifestation15 (60%)10 (59%)5 (62%)
Cardiac involvement17 (68%)11 (65%)6 (75%)
Pulmonary fibrosis11 (44%)7 (41%)4 (50%)
Renal abnormalities4 (16%)1 (6%)3 (37%)
Hematological involvement6 (24%)4 (23%)2 (25%)
Arthralgia19 (76%)13 (76%)6 (75%)

Results are shown as number and percent. Duration is presented in years as of the mean. Abbreviations: SSc: scleroderma; lSSc: limited systemic sclerosis; dSSc: diffuse systemic sclerosis; SD: standard deviation.