Research Article

The Role of Angiogenesis Factors in the Formation of Vascular Changes in Scleroderma by Assessment of the Concentrations of VEGF and sVEGFR2 in Blood Serum and Tear Fluid

Table 2

Characteristics of vascular changes of the eye fundus and the presence of peripheral trophic changes in patients with scleroderma.

Vascular changes of the eye fundusNumber of eyes in SSc patients groupFingers ulcerations
lSSc
()
dSSc
()
SSc
()
Observed
(number of patients)
Not observed
(number of patients)

AMD (soft drusen and window defects of retinal pigment epithelium)11314142
Hard exudates24621
Irregularities in the course and caliber of the retinal vessels22830123
Delayed filling of choroidal lobules1462091
Occlusion of the peripheral arterial vessel20220
Sheathed venous vessel01110
Thinning of choroidal capillaries and retinal pigment epithelium42630
Ischemic retinopathy22411
Normal fundus62871

Abbreviations: lSSc: limited systemic sclerosis; dSSc: diffuse systemic sclerosis; AMD: age-related macular degeneration.