Research Article

The Role of MIF-173G/C Gene Polymorphism in the Susceptibility of Autoimmune Diseases

Table 3

The summary of the results from different comparative genetic models in different areas.

AreasGenetic models (%)Effects modelOR (95% CI)Egger’s regression analysisBegg’s regression analysis

AsiaC/G49.50.01FIX1.40 (1.28, 1.54)7.280.01-0.220.79-0.870.38
CC/GG00.84FIX1.91 (1.55, 2.38)6.030.011.790.151.100.27
GC/GG00.57FIX1.29 (1.15, 1.44)4.390.01-1.100.03-1.780.08
CC+GC/GG14.10.29FIX1.38 (1.23, 1.53)5.760.010.340.390.420.68
CC/GC+GG26.30.15FIX2.32 (1.79, 3.00)6.420.011.460.290.870.38

EuropeC/G27.80.20FIX1.21 (1.06, 1.37)2.870.011.950.300.420.68
CC/GG5.30.39FIX1.56 (1.10, 2.21)2.520.010.160.9201
GC/GG11.30.34FIX1.51 (0.99, 1.35)1.810.701.520.3601
CC+GC/GG14.90.31FIX1.20 (1.03, 1.39)2.360.01-0.020.811.040.30
CC/GC+GG100.35FIX1.58 (1.09, 2.29)2.430.02-0.220.89-0.210.84

North AmericaC/G00.72FIX1.28 (1.10, 1.48)3.170.01-8.79___-1.000.32
CC/GG00.40FIX1.30 (0.80, 2.12)1.050.29-8.79___-1.000.32
GC/GG00.59FIX1.38 (1.16, 1.65)3.640.01134.28___1.000.32
CC+GC/GG00.77FIX1.38 (1.16, 1.63)3.710.010.08___1.000.32
CC/GC+GG00.37FIX1.21 (0.73, 2.00)0.750.45-0.87___-1.000.32