Research Article

Higher Serum Neuropeptide Y Levels Are Associated with Metabolically Unhealthy Obesity in Obese Chinese Adults: A Cross-Sectional Study

Table 1

Baseline characteristics of the study participants ().

CharacteristicAll ()Obesity
MHO ()MUO ()

Age (years)44.53 (14.04)39.94 (13.09)48.03 (13.78)<0.001
Sex0.488
 Male120 (73.0%)50 (70.4%)70 (75.3%)
 Female44 (27.0%)21 (29.6%)23 (24.7%)
BMI (kg/m2)28.11 (2.51)27.78(2.38)28.50 (2.46)0.061
WC (cm)92.15 (6.80)89.23 (4.50)94.39 (7.41)<0.001
WHR0.94 (0.06)0.93 (0.06)0.96 (0.06)0.003
SBP (mmHg)133.24 (18.66)121.68 (12.17)142.06 (17.96)<0.001
DBP (mmHg)81.66 (11.90)75.08 (8.76)86.69 (11.56)<0.001
TG (mmol/L)1.67 (1.12-2.78)1.19 (0.90-1.37)2.35 (1.73-3.33)<0.001
TC (mmol/L)4.83 (1.13)4.49 (0.70)5.09 (1.32)<0.001
HDL-C (mmol/L)1.18 (0.30)1.32 (0.24)1.08 (0.31)<0.001
LDL-C (mmol/L)2.88 (0.93)2.63 (0.65)3.07 (1.05)<0.001
FBS (mmol/L)5.45 (5.05-7.14)5.08 (4.78-5.29)6.46 (5.54-9.18)<0.001
NEFA (mmol/L)0.49 (0.25)0.45 (0.15)0.51 (0.29)0.174
HbA1C (%)5.60 (5.30-6.67)5.30 (5.10-5.50)6.40 (5.60-7.90)<0.001
NPY(pg/mL)585.95 (257.93)478.89 (145.53)667.69(292.90)<0.001

Data were reported as the mean (SD) or median (IQR: Q1-Q3). The -test or Mann-Whitney test or test was used for comparisons between MHO group and MUO group.
MHO: metabolically healthy obese; MUO: metabolically unhealthy obese; WC: waist circumference; WHR: waist to hip measurement ratio; BMI: body mass index; SBP: systolic blood pressure; DBP: diastolic blood pressure; FBS: fasting blood sugar; TG: triglycerides; TC: total cholesterol; HDL-C: high-density lipoprotein-cholesterol; LDL-C: low-density lipoprotein-cholesterol; NEFA: nonesterified fatty acids.