ASK1 Enhances Angiotensin II-Induced Liver Fibrosis <i>In Vitro</i> by Mediating Endoplasmic Reticulum Stress-Dependent Exosomes

<div>ERS caused exosome release from activated HSC cells. Exosomes released by LX-2 cells in the Ang II and blank groups were detected by electron microscopy (a). (b) Western blot analysis of <i>α</i>-SMA expression in exosomes released by LX-2 cells in the Ang II and blank groups. PKH-26-labeled exosomes (red) were taken up by LX-2 cells (c). Scale bar, 100 nm. Western blotting (d) and immunofluorescence staining (e) of <i>α</i>-SMA in quiescent HSC cells after incubated with exosomes released from activated HSC cells. 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Mediators of Inflammation

fig3

Figure 3

Figure 3: ASK1 Enhances Angiotensin II-Induced Liver Fibrosis <i>In Vitro</i> by Mediating Endoplasmic Reticulum Stress-Dependent Exosomes 

Mediators of Inflammation

ASK1 Enhances Angiotensin II-Induced Liver Fibrosis In Vitro by Mediating Endoplasmic Reticulum Stress-Dependent Exosomes

Figure 3