ASK1 Enhances Angiotensin II-Induced Liver Fibrosis <i>In Vitro</i> by Mediating Endoplasmic Reticulum Stress-Dependent Exosomes

<div>Effects of an ASK1 inhibitor on ERS-induced exosome release by activated HSC cells. LX-2 cells were treated with Ang II alone or cotreated with Ang II and an ASK1 inhibitor (GS-4997). Western blotting (a) and immunofluorescence staining (b) of <i>α</i>-SMA are shown in quiescent HSC cells incubated with activated HSCs. Western blotting (c) and immunofluorescence staining (d) of <i>α</i>-SMA are shown in quiescent HSCs cocultured with activated HSCs. 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Mediators of Inflammation

fig7

Figure 7

Figure 7: ASK1 Enhances Angiotensin II-Induced Liver Fibrosis <i>In Vitro</i> by Mediating Endoplasmic Reticulum Stress-Dependent Exosomes 

Mediators of Inflammation

ASK1 Enhances Angiotensin II-Induced Liver Fibrosis In Vitro by Mediating Endoplasmic Reticulum Stress-Dependent Exosomes

Figure 7