Trained Innate Immunity by Repeated Low-Dose Lipopolysaccharide Injections Displays Long-Term Neuroprotective Effects

<div>Effects of repeated LPS injections and CLP on hippocampal cytokines. Tissue ELISA showed increased IL-1<i>β</i> and IL-6 levels in the hippocampus following CLP, which were prevented by repeated LPS injections. 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LPS: lipopolysaccharide; CLP: cecal ligation and puncture; Veh: vehicle.</div>

Mediators of Inflammation

fig4

Figure 4

Figure 4: Trained Innate Immunity by Repeated Low-Dose Lipopolysaccharide Injections Displays Long-Term Neuroprotective Effects 