Mediators of Inflammation

Research Article

Diagnostic and Prognostic Value of IL-6 and sTREM-1 in SIRS and Sepsis in Children

Table 1

Demographic and clinical characteristics in the study and control groups.


Characteristics	Study group ()	Control group ()	value	Study group			value
Characteristics	Study group ()	Control group ()	value	N-SIRS ()	SIRS ()	Sepsis ()	value

Sex
Male	101 (56.1)	28 (57.1)	0.897	45 (54.9)	34 (64.2)	22 (48.9)	0.302
Female	79 (43.9)	21 (42.9)	0.897	37 (45.1)	19 (35.8)	23 (51.1)	0.302
Age (years)			0.549				0.587
Hospitalization (days)			<0.001				<0.001
Prolonged days after admission		—	—				0.154
CRP (mg/l)	24.9 (7.6-65.4)	1 (0.3-4.2)	<0.001	17.9 (7.9-58.9)	28.7 (6.9-71.8)	34.4 (8.7-74.2)	0.243
PCT (ng/ml)	0.6 (0.2-1.6)	0 (0-0.1)	<0.001	0.31 (0.1-0.2)	0.8 (0.341.7)	1.15 (0.5-3.0)	<0.001
IL-6 (pg/ml)	21.4 (10.5-53.3)	3.48 (1.8-6.2)	<0.001	18.1 (8.5-29.2)	32.6 (13.8-94.0)	26.4 (11.5-71.4)	0.013
sTREM-1 (pg/ml)	18.7 (18.7-34.3)	18.7 (18.7-18.7)	0.005	18.7 (18.7-27.4)	18.7 (18.7-27.3)	21.8 (18.7-40.2)	0.098

Quantitative data are expressed as or median (interquartile range). Qualitative data are expressed as number (percentage). CRP: C-reactive protein; PCT: procalcitonin; IL-6: interleukin-6; sTREM-1: soluble triggering receptor expressed on myeloid cells-1.