MEG3 Alleviated LPS-Induced Intestinal Injury in Sepsis by Modulating miR-129-5p and Surfactant Protein D

<div>SP-D was a direct target of miR-129-5p. (a) Binding sites between SP-D and miR-129-5p. (b) The luciferase reporter constructs containing the wild-type (WT-SP-D) or mutant SP-D (MUT-SP-D) sequence. (c) WT-SP-D or MUT-SP-D was cotransfected into HEK-293T cells with miR-129-5p mimics or their corresponding negative controls. Three independent experiments were carried out. 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Mediators of Inflammation

fig6

Figure 6

Figure 6: MEG3 Alleviated LPS-Induced Intestinal Injury in Sepsis by Modulating miR-129-5p and Surfactant Protein D 