miR-199a-5p Exacerbated Intestinal Barrier Dysfunction through Inhibiting Surfactant Protein D and Activating NF-κB Pathway in Sepsis

Figure 3

Intestinal mucosa permeability in sepsis mice models was affected by miR-199a-5p. (a) miR-199a-5p expression in the sepsis mice intestine tissues. Sepsis mice were treated with miR-199a-5p mimic or inhibitor. (b) Levels of DAO in serum of sepsis mice after treating with miR-199a-5p mimic or inhibitor. (c) Levels of D-lactic acid in serum of sepsis mice after treating with miR-199a-5p mimic or inhibitor. (d) Levels of FD-40 in serum of sepsis mice after treating with miR-199a-5p mimic or inhibitor. Three independent experiments were carried out. Error bars stand for the of at least triplicate experiments. .

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